May 12, 2018

In patients who are elderly, volume-depleted including those on diuretic therapy , or with compromised renal function, co-administration of nsaids, including selective cox-2 inhibitors, with ace inhibitors, including lisinopril, may result in deterioration of renal function, including possible acute renal failure.

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in these patients, lisinopril tablets should be started under very close medical supervision and such patients should be followed closely for the first two weeks of treatment and whenever the dose of lisinopril tablets and or diuretic is increased.

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