The prevalence rates presented below are based on combined data from placebo-controlled studies involving once-daily administration of doxazosin at doses ranging from 1 mg to 16 mg.
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concomitant administration of doxazosin tablets with a pde-5 inhibitor can result in additive blood pressure lowering effects and symptomatic hypotension; therefore, pde-5 inhibitor therapy should be initiated at the lowest dose in patients taking doxazosin tablets.
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blood pressure was measured manually pre-dose at two time points -30 and -15 minutes and then at 1, 2, 3, 4, 5, 6, 7, 8, 10, 12 and 24 hours post dose on the first day of each doxazosin dose, 1 mg, 2 mg, 4 mg , as well as on the seventh day of 4 mg doxazosin administration.
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